REPS2

Gene Information
  • Official Symbol: REPS2
  • Official Name: RALBP1 associated Eps domain containing 2
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 9185
  • UniProt: Q8NFH8
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: The product of this gene is part of a protein complex that regulates the endocytosis of growth factor receptors. The encoded protein directly interacts with a GTPase activating protein that functions downstream of the small G protein Ral. Its expression can negatively affect receptor internalization and inhibit growth factor signaling. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
  • UniProt Summary: Involved in growth factor signaling through its influence on the Ral signaling pathway.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 7579
  • Expression level (log2 read counts): 3.52

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1