RPS18

Entrez Summary: N/A
UniProt Summary: Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 624/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	1/1
909776.0	0/1
bile duct	24/28
blood	20/28
bone	22/26
breast	29/33
central nervous system	51/56
cervix	3/4
colorectal	16/17
esophagus	10/13
fibroblast	0/1
gastric	14/16
kidney	17/21
liver	18/20
lung	64/75
lymphocyte	14/16
ovary	24/26
pancreas	22/24
peripheral nervous system	13/16
plasma cell	13/15
prostate	1/1
skin	23/24
soft tissue	8/9
thyroid	2/2
upper aerodigestive	14/22
urinary tract	23/29
uterus	5/5

Expression Distribution

Gene	Correlation
HGC6.3	0.656
RPS16	0.404

small ribosomal subunit
rRNA binding
ribosome
cytosolic small ribosomal subunit
SRP-dependent cotranslational protein targeting to membrane
cotranslational protein targeting to membrane
protein targeting to ER
establishment of protein localization to endoplasmic reticulum
viral transcription
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
viral gene expression
protein localization to endoplasmic reticulum
translational initiation
protein targeting to membrane
structural constituent of ribosome
nuclear-transcribed mRNA catabolic process
mRNA catabolic process
RNA catabolic process
postsynaptic density
establishment of protein localization to membrane
protein targeting
nucleobase-containing compound catabolic process
translation
peptide biosynthetic process
focal adhesion
establishment of protein localization to organelle
heterocycle catabolic process
cellular nitrogen compound catabolic process
aromatic compound catabolic process
organic cyclic compound catabolic process
protein localization to membrane
amide biosynthetic process
peptide metabolic process
mRNA metabolic process
viral process
protein localization to organelle
symbiotic process
cellular amide metabolic process
interspecies interaction between organisms
cellular macromolecule catabolic process