S100A11

Entrez Summary: N/A
UniProt Summary: Facilitates the differentiation and the cornification of keratinocytes. {ECO:0000269|PubMed:18618420}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

S 100
efhand

S100 protein binding
cadherin binding involved in cell-cell adhesion
negative regulation of DNA replication
calcium-dependent protein binding
ruffle
cell-cell adherens junction
regulation of DNA replication
secretory granule lumen
neutrophil degranulation
neutrophil activation involved in immune response
neutrophil mediated immunity
neutrophil activation
cell-cell adhesion
granulocyte activation
leukocyte degranulation
myeloid leukocyte mediated immunity
myeloid cell activation involved in immune response
myeloid leukocyte activation
leukocyte activation involved in immune response
cell activation involved in immune response
negative regulation of cell population proliferation
regulated exocytosis
calcium ion binding
leukocyte mediated immunity
exocytosis
protein homodimerization activity
leukocyte activation
cell adhesion
biological adhesion
secretion by cell
export from cell
cell activation
immune effector process
secretion
negative regulation of cellular macromolecule biosynthetic process
negative regulation of macromolecule biosynthetic process
negative regulation of cellular biosynthetic process
negative regulation of biosynthetic process
extracellular space
regulation of cell population proliferation