SAMD5

Gene Information

Official Symbol: SAMD5
Official Name: sterile alpha motif domain containing 5
Aliases and Previous Symbols: N/A
Entrez ID: 389432
UniProt: Q5TGI4
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Function Summary

Entrez Summary: N/A
UniProt Summary: N/A

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Essentiality in NALM6

Essentiality Rank: 11326
Expression level (log2 read counts): 2.78

Expression Distribution

SAM 1
SAM 2

mitogen-activated protein kinase kinase kinase binding
positive regulation of JUN kinase activity
positive regulation of NIK/NF-kappaB signaling
regulation of JUN kinase activity
regulation of NIK/NF-kappaB signaling
positive regulation of JNK cascade
positive regulation of stress-activated MAPK cascade
positive regulation of stress-activated protein kinase signaling cascade
regulation of JNK cascade
regulation of stress-activated MAPK cascade
regulation of stress-activated protein kinase signaling cascade
positive regulation of MAP kinase activity
positive regulation of protein serine/threonine kinase activity
regulation of MAP kinase activity
regulation of protein serine/threonine kinase activity
positive regulation of protein kinase activity
positive regulation of MAPK cascade
positive regulation of kinase activity
positive regulation of transferase activity
regulation of cellular response to stress
regulation of MAPK cascade
regulation of protein kinase activity
regulation of kinase activity
regulation of transferase activity
positive regulation of protein phosphorylation
positive regulation of intracellular signal transduction
positive regulation of phosphorylation
positive regulation of phosphorus metabolic process
positive regulation of phosphate metabolic process
positive regulation of protein modification process
positive regulation of catalytic activity
regulation of protein phosphorylation
regulation of response to stress
regulation of phosphorylation
positive regulation of cellular protein metabolic process
positive regulation of signal transduction
positive regulation of protein metabolic process
positive regulation of molecular function
regulation of phosphate metabolic process
regulation of phosphorus metabolic process