SDK2

Gene Information
  • Official Symbol: SDK2
  • Official Name: sidekick cell adhesion molecule 2
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 54549
  • UniProt: Q58EX2
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Adhesion molecule that promotes lamina-specific synaptic connections in the retina and is specifically required for the formation of neuronal circuits that detect motion. Acts by promoting formation of synapses between two specific retinal cell types: the retinal ganglion cells W3B-RGCs and the excitatory amacrine cells VG3-ACs. Formation of synapses between these two cells plays a key role in detection of motion. Promotes synaptic connectivity via homophilic interactions. {ECO:0000250|UniProtKB:Q6V4S5}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 4297
  • Expression level (log2 read counts): 1.15

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1