SEMA3B

Gene Information
  • Official Symbol: SEMA3B
  • Official Name: semaphorin 3B
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 7869
  • UniProt: Q13214
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: The protein encoded by this gene belongs to the class-3 semaphorin/collapsin family, whose members function in growth cone guidance during neuronal development. This family member inhibits axonal extension and has been shown to act as a tumor suppressor by inducing apoptosis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2014].
  • UniProt Summary: Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. {ECO:0000250}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 9600
  • Expression level (log2 read counts): 0.4

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1