SEPT5

Entrez Summary: N/A
UniProt Summary: Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). May play a role in platelet secretion (By similarity). {ECO:0000250, ECO:0000305}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

synaptic vesicle targeting
septin ring
septin complex
social behavior
intraspecies interaction between organisms
synaptic vesicle exocytosis
multi-organism behavior
exocytic process
regulation of synaptic vesicle exocytosis
vesicle targeting
cytoskeleton-dependent cytokinesis
cytokinesis
neurotransmitter secretion
signal release from synapse
regulation of neurotransmitter secretion
regulation of synaptic vesicle cycle
synaptic vesicle cycle
synaptic vesicle
vesicle-mediated transport in synapse
regulation of neurotransmitter transport
adult behavior
microtubule cytoskeleton
regulation of regulated secretory pathway
signal release
establishment of vesicle localization
neurotransmitter transport
vesicle localization
structural molecule activity
regulation of exocytosis
GTPase activity
regulation of neurotransmitter levels
establishment of organelle localization
GTP binding
anterograde trans-synaptic signaling
chemical synaptic transmission
trans-synaptic signaling
modulation of chemical synaptic transmission
regulation of trans-synaptic signaling
synaptic signaling
cell division