SIGLEC15

Entrez Summary: N/A
UniProt Summary: Binds sialylated glycoproteins. {ECO:0000269|PubMed:17483134}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

regulation of osteoclast development
regulation of bone development
regulation of bone resorption
regulation of bone remodeling
regulation of osteoclast differentiation
regulation of tissue remodeling
regulation of myeloid leukocyte differentiation
regulation of myeloid cell differentiation
regulation of leukocyte differentiation
regulation of actin cytoskeleton organization
regulation of actin filament-based process
regulation of hemopoiesis
regulation of cytoskeleton organization
protein-containing complex
innate immune response
regulation of cell development
defense response to other organism
regulation of organelle organization
response to other organism
response to external biotic stimulus
response to biotic stimulus
defense response
regulation of immune system process
regulation of cell differentiation
immune response