SLC1A7

Entrez Summary: N/A
UniProt Summary: Transports L-glutamate; the L-glutamate uptake is sodium- and voltage-dependent and chloride-independent. Its associated chloride conductance may participate in visual processing.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

L-glutamate transmembrane transporter activity
neurotransmitter reuptake
L-glutamate transmembrane transport
glutamate secretion
neurotransmitter uptake
symporter activity
L-alpha-amino acid transmembrane transport
acidic amino acid transport
L-amino acid transport
drug transmembrane transport
amino acid transmembrane transport
dicarboxylic acid transport
acid secretion
presynapse
amino acid transport
carboxylic acid transmembrane transport
organic acid transmembrane transport
drug transport
neurotransmitter transport
anion transmembrane transport
organic acid transport
carboxylic acid transport
regulation of neurotransmitter levels
organic anion transport
anion transport
import into cell
ion transmembrane transport
secretion by cell
response to drug
export from cell
secretion
transmembrane transport
ion transport
establishment of localization in cell
nitrogen compound transport