SLC35B2
Gene Information
- Official Symbol: SLC35B2
- Official Name: solute carrier family 35 member B2
- Aliases and Previous Symbols: N/A
- Entrez ID: 347734
- UniProt: Q8TB61
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
| UAA |
| EamA |
GO Terms
| 3-phosphoadenosine 5-phosphosulfate transmembrane transporter activity |
| 3-phosphoadenosine 5-phosphosulfate transport |
| 3-phospho-5-adenylyl sulfate transmembrane transport |
| purine ribonucleoside bisphosphate biosynthetic process |
| 3-phosphoadenosine 5-phosphosulfate biosynthetic process |
| nucleotide transmembrane transport |
| purine-containing compound transmembrane transport |
| adenine nucleotide transport |
| purine ribonucleotide transport |
| purine nucleotide transport |
| nucleotide transport |
| 3-phosphoadenosine 5-phosphosulfate metabolic process |
| purine ribonucleoside bisphosphate metabolic process |
| sulfur compound transport |
| nucleoside bisphosphate biosynthetic process |
| purine nucleoside bisphosphate biosynthetic process |
| ribonucleoside bisphosphate biosynthetic process |
| transmembrane transporter activity |
| integral component of Golgi membrane |
| carbohydrate derivative transport |
| integral component of endoplasmic reticulum membrane |
| organophosphate ester transport |
| ribonucleoside bisphosphate metabolic process |
| purine nucleoside bisphosphate metabolic process |
| nucleoside bisphosphate metabolic process |
| purine ribonucleotide biosynthetic process |
| purine nucleotide biosynthetic process |
| ribonucleotide biosynthetic process |
| ribose phosphate biosynthetic process |
| purine-containing compound biosynthetic process |
| sulfur compound biosynthetic process |
| positive regulation of I-kappaB kinase/NF-kappaB signaling |
| regulation of I-kappaB kinase/NF-kappaB signaling |
| nucleobase-containing compound transport |
| nucleotide biosynthetic process |
| nucleoside phosphate biosynthetic process |
| anion transmembrane transport |
| purine ribonucleotide metabolic process |
| ribonucleotide metabolic process |
| purine nucleotide metabolic process |
| ribose phosphate metabolic process |
| sulfur compound metabolic process |
| purine-containing compound metabolic process |
| nucleotide metabolic process |
| nucleoside phosphate metabolic process |
| organic anion transport |
| organophosphate biosynthetic process |
| nucleobase-containing small molecule metabolic process |
| anion transport |
| carbohydrate derivative biosynthetic process |
| Golgi membrane |
| organophosphate metabolic process |
| ion transmembrane transport |
| Golgi apparatus |
| oxoacid metabolic process |
| positive regulation of intracellular signal transduction |
| organic acid metabolic process |
| carbohydrate derivative metabolic process |
| nucleobase-containing compound biosynthetic process |
| heterocycle biosynthetic process |
| aromatic compound biosynthetic process |
| transmembrane transport |
| organic cyclic compound biosynthetic process |
| ion transport |
| organonitrogen compound biosynthetic process |
| cellular nitrogen compound biosynthetic process |
| positive regulation of signal transduction |
| small molecule metabolic process |
| positive regulation of cell communication |
| positive regulation of signaling |
| regulation of intracellular signal transduction |
| nitrogen compound transport |
| membrane |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
| Screen | Score |
|---|---|
| Hypoxia 5%O2 R04 exp191 | 1.91 |
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 19/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 1/1 |
| 909776.0 | 1/1 |
| bile duct | 1/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 3/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 3/20 |
| lung | 1/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 1/16 |
| plasma cell | 2/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 2/22 |
| urinary tract | 2/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 7400
- Expression level (log2 read counts): 5.24
Expression Distribution
SLC35B2 Expression in NALM6 Cells: 5.24
