SLC36A2

Gene Information
  • Official Symbol: SLC36A2
  • Official Name: solute carrier family 36 member 2
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 153201
  • UniProt: Q495M3
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: This gene encodes a pH-dependent proton-coupled amino acid transporter that belongs to the amino acid auxin permease 1 protein family. The encoded protein primarily transports small amino acids such as glycine, alanine and proline. Mutations in this gene are associated with iminoglycinuria and hyperglycinuria. [provided by RefSeq, Sep 2010].
  • UniProt Summary: Involved in a pH-dependent electrogenic neuronal transport and sequestration of small amino acids. Transports glycine and proline. Inhibited by sarcosine (By similarity). {ECO:0000250, ECO:0000269|PubMed:19033659}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 10342
  • Expression level (log2 read counts): 2.42

Expression Distribution

  • Last modified: 2025/12/10 20:19
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