SLC50A1

Entrez Summary: N/A
UniProt Summary: Mediates sugar transport across membranes. May stimulate V(D)J recombination by the activation of RAG1. {ECO:0000269|PubMed:21107422}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
Trimetrexate 0.03μM R08 exp535	1.78
Rapamycin 10μM R00 exp30	2.04

glucoside transmembrane transporter activity
glucoside transport
glycoside transport
sugar transmembrane transporter activity
hexose transmembrane transport
monosaccharide transmembrane transport
carbohydrate transmembrane transport
carbohydrate derivative transport
endomembrane system
carbohydrate transport
Golgi membrane
Golgi apparatus
transmembrane transport