SLIRP
Gene Information
- Official Symbol: SLIRP
- Official Name: SRA stem-loop interacting RNA binding protein
- Aliases and Previous Symbols: N/A
- Entrez ID: 81892
- UniProt: Q9GZT3
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: RNA-binding protein that acts as a nuclear receptor corepressor. Probably acts by binding the SRA RNA, and repressing the SRA-mediated nuclear receptor coactivation. Binds the STR7 loop of SRA RNA. Also able to repress glucocorticoid (GR), androgen (AR), thyroid (TR) and VDR-mediated transactivation. {ECO:0000269|PubMed:16762838}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 1892
- Expression level (log2 read counts): 5.58