SMYD1

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/726

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/25
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/15
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/14
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/7
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

SET
zf-MYND

histone-lysine N-methyltransferase activity
positive regulation of myoblast differentiation
positive regulation of myotube differentiation
skeletal muscle cell differentiation
regulation of myoblast differentiation
regulation of myotube differentiation
positive regulation of striated muscle cell differentiation
histone lysine methylation
positive regulation of muscle cell differentiation
peptidyl-lysine methylation
histone methylation
regulation of striated muscle cell differentiation
skeletal muscle tissue development
skeletal muscle organ development
protein methylation
protein alkylation
regulation of muscle cell differentiation
chromatin remodeling
transcription corepressor activity
macromolecule methylation
striated muscle tissue development
muscle organ development
muscle tissue development
methylation
peptidyl-lysine modification
histone modification
covalent chromatin modification
muscle structure development
heart development
chromatin organization
circulatory system development
peptidyl-amino acid modification
positive regulation of cell differentiation
chromosome organization
negative regulation of transcription, DNA-templated
negative regulation of nucleic acid-templated transcription
negative regulation of RNA biosynthetic process
negative regulation of RNA metabolic process
positive regulation of developmental process
negative regulation of cellular macromolecule biosynthetic process