SPHKAP

Gene Information
  • Official Symbol: SPHKAP
  • Official Name: SPHK1 interactor, AKAP domain containing
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 80309
  • UniProt: Q2M3C7
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Anchoring protein that binds preferentially to the type I regulatory subunit of c-AMP-dependent protein kinase (PKA type I) and targets it to distinct subcellular compartments. May act as a converging factor linking cAMP and sphingosine signaling pathways. Plays a regulatory role in the modulation of SPHK1. {ECO:0000269|PubMed:12080051, ECO:0000269|PubMed:20394097}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 8553
  • Expression level (log2 read counts): -4.6

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1