STEAP3

Gene Information
  • Official Symbol: STEAP3
  • Official Name: STEAP3 metalloreductase
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 55240
  • UniProt: Q658P3
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: This gene encodes a multipass membrane protein that functions as an iron transporter. The encoded protein can reduce both iron (Fe3+) and copper (Cu2+) cations. This protein may mediate downstream responses to p53, including promoting apoptosis. Deficiency in this gene can cause anemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015].
  • UniProt Summary: N/A

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 12047
  • Expression level (log2 read counts): -2.74

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1