STK17B

Entrez Summary: N/A
UniProt Summary: Phosphorylates myosin light chains (By similarity). Acts as a positive regulator of apoptosis. {ECO:0000250, ECO:0000269|PubMed:9786912}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Pkinase Tyr
Pkinase

positive regulation of fibroblast apoptotic process
regulation of fibroblast apoptotic process
endoplasmic reticulum-Golgi intermediate compartment
protein autophosphorylation
actin cytoskeleton
protein kinase activity
protein serine/threonine kinase activity
positive regulation of apoptotic process
positive regulation of programmed cell death
positive regulation of cell death
apoptotic process
protein phosphorylation
programmed cell death
cell death
phosphorylation
ATP binding
regulation of apoptotic process
regulation of programmed cell death
regulation of cell death
intracellular signal transduction