STX19

Entrez Summary: N/A
UniProt Summary: Plays a role in endosomal trafficking of the epidermal growth factor receptor (EGFR). {ECO:0000250|UniProtKB:Q8R1Q0}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Syntaxin
SNARE

presynaptic active zone membrane
synaptic vesicle fusion to presynaptic active zone membrane
vesicle fusion to plasma membrane
SNAP receptor activity
SNARE complex
vesicle docking
synaptic vesicle exocytosis
SNARE binding
exocytic process
vesicle fusion
presynaptic membrane
endomembrane system
organelle membrane fusion
organelle fusion
signal release from synapse
neurotransmitter secretion
synaptic vesicle cycle
synaptic vesicle
vesicle-mediated transport in synapse
membrane fusion
signal release
organelle localization by membrane tethering
membrane docking
neurotransmitter transport
vesicle organization
regulation of neurotransmitter levels
anterograde trans-synaptic signaling
chemical synaptic transmission
trans-synaptic signaling
synaptic signaling
organelle localization
regulated exocytosis
exocytosis
membrane organization
intracellular protein transport
secretion by cell
export from cell
cell-cell signaling
secretion
protein transport