STXBP6

Entrez Summary: N/A
UniProt Summary: Forms non-fusogenic complexes with SNAP25 and STX1A and may thereby modulate the formation of functional SNARE complexes and exocytosis.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

exocyst localization
regulation of SNARE complex assembly
cadherin binding involved in cell-cell adhesion
exocyst
GTP-Rho binding
cellular protein-containing complex localization
regulation of vesicle fusion
negative regulation of exocytosis
Golgi to plasma membrane transport
phosphatidylinositol-4,5-bisphosphate binding
vesicle-mediated transport to the plasma membrane
post-Golgi vesicle-mediated transport
cell-cell adherens junction
negative regulation of secretion by cell
regulation of exocytosis
negative regulation of secretion
protein-containing complex localization
Golgi vesicle transport
regulation of protein complex assembly
negative regulation of transport
cell-cell adhesion
regulation of vesicle-mediated transport
regulation of secretion by cell
exocytosis
regulation of secretion
cell adhesion
biological adhesion
regulation of cellular component biogenesis
secretion by cell
export from cell
secretion
regulation of organelle organization
cellular protein localization
cellular macromolecule localization
regulation of transport
vesicle-mediated transport