SYDE1

Gene Information
  • Official Symbol: SYDE1
  • Official Name: synapse defective Rho GTPase homolog 1
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 85360
  • UniProt: Q6ZW31
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: GTPase activator for the Rho-type GTPases. As a GCM1 downstream effector, it is involved in placental development and positively regulates trophoblast cells migration. It regulates cytoskeletal remodeling by controlling the activity of Rho GTPases including RHOA, CDC42 and RAC1 (PubMed:27917469). {ECO:0000269|PubMed:27917469}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 3487
  • Expression level (log2 read counts): -3.08

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1