SYNDIG1

Entrez Summary: N/A
UniProt Summary: May regulate AMPA receptor content at nascent synapses, and have a role in postsynaptic development and maturation. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

glutamate receptor binding
synaptic vesicle clustering
excitatory synapse
dendritic shaft
synaptic vesicle localization
positive regulation of synapse assembly
cell body
presynapse
regulation of synapse assembly
synaptic vesicle cycle
vesicle-mediated transport in synapse
dendritic spine
early endosome membrane
vesicle localization
postsynaptic membrane
regulation of synapse organization
regulation of synapse structure or activity
postsynaptic density
positive regulation of cellular component biogenesis
positive regulation of nervous system development
cell junction
organelle localization
intracellular membrane-bounded organelle
protein homodimerization activity
regulation of nervous system development
regulation of cellular component biogenesis
intracellular protein transport
positive regulation of cellular component organization
positive regulation of developmental process
integral component of plasma membrane
protein transport
intracellular transport
peptide transport
amide transport
cellular protein localization
cellular macromolecule localization
establishment of protein localization
positive regulation of multicellular organismal process
establishment of localization in cell
nitrogen compound transport