SYNPO2L

Entrez Summary: N/A
UniProt Summary: Actin-associated protein that may play a role in modulating actin-based shape. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

positive regulation of Rho protein signal transduction
sarcomere organization
positive regulation of stress fiber assembly
positive regulation of actin filament bundle assembly
positive regulation of Ras protein signal transduction
myofibril assembly
positive regulation of small GTPase mediated signal transduction
regulation of stress fiber assembly
regulation of actomyosin structure organization
regulation of actin filament bundle assembly
cellular component assembly involved in morphogenesis
actomyosin structure organization
Z disc
striated muscle cell development
regulation of Rho protein signal transduction
muscle cell development
positive regulation of supramolecular fiber organization
striated muscle cell differentiation
actin cytoskeleton
positive regulation of cytoskeleton organization
regulation of Ras protein signal transduction
muscle cell differentiation
heart morphogenesis
regulation of actin filament organization
actin binding
regulation of actin cytoskeleton organization
regulation of small GTPase mediated signal transduction
regulation of supramolecular fiber organization
regulation of actin filament-based process
nuclear speck
supramolecular fiber organization
muscle structure development
actin cytoskeleton organization
positive regulation of cellular component biogenesis
heart development
regulation of cytoskeleton organization
cell junction
actin filament-based process
positive regulation of organelle organization
organelle assembly