TEX11

Entrez Summary: This gene is X-linked and is expressed in only male germ cells. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
UniProt Summary: Regulator of crossing-over during meiosis. Involved in initiation and/or maintenance of chromosome synapsis and formation of crossovers (By similarity). {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/694

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/26
bone	0/26
breast	0/30
central nervous system	0/49
cervix	0/4
colorectal	0/17
esophagus	0/11
fibroblast	0/1
gastric	0/14
kidney	0/18
liver	0/19
lung	0/72
lymphocyte	0/16
ovary	0/25
pancreas	0/22
peripheral nervous system	0/15
plasma cell	0/12
prostate	0/1
skin	0/20
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/28
uterus	0/5

Expression Distribution

meiotic gene conversion
male meiosis chromosome segregation
gene conversion
chiasma assembly
central element
resolution of meiotic recombination intermediates
synaptonemal complex assembly
meiotic chromosome separation
synaptonemal complex organization
synaptonemal complex
chromosome separation
synapsis
male meiotic nuclear division
reciprocal meiotic recombination
homologous recombination
homologous chromosome segregation
chromosome organization involved in meiotic cell cycle
meiotic chromosome segregation
meiosis I
meiosis I cell cycle process
male gonad development
development of primary male sexual characteristics
meiotic nuclear division
male sex differentiation
meiotic cell cycle process
fertilization
gonad development
development of primary sexual characteristics
nuclear chromosome segregation
DNA recombination
meiotic cell cycle
sex differentiation
chromosome segregation
nuclear division
organelle fission
cellular process involved in reproduction in multicellular organism
reproductive structure development
reproductive system development
male gamete generation
developmental process involved in reproduction