TMEM176B

Entrez Summary: N/A
UniProt Summary: May play a role in the process of maturation of dendritic cells. Required for the development of cerebellar granule cells (By similarity). {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

negative regulation of dendritic cell differentiation
regulation of dendritic cell differentiation
negative regulation of leukocyte differentiation
negative regulation of hemopoiesis
nuclear membrane
regulation of leukocyte differentiation
negative regulation of immune system process
regulation of hemopoiesis
negative regulation of cell differentiation
negative regulation of developmental process
animal organ morphogenesis
negative regulation of multicellular organismal process
regulation of immune system process
regulation of cell differentiation