TMEM59L

Gene Information
  • Official Symbol: TMEM59L
  • Official Name: transmembrane protein 59 like
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 25789
  • UniProt: Q9UK28
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Modulates the O-glycosylation and complex N- glycosylation steps occurring during the Golgi maturation of APP. Inhibits APP transport to the cell surface and further shedding. {ECO:0000269|PubMed:20427278}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 9457
  • Expression level (log2 read counts): -4.6

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1