TNFSF12-TNFSF13
Gene Information
- Official Symbol: N/A
- Official Name: N/A
- Aliases and Previous Symbols: N/A
- Entrez ID: N/A
- UniProt: N/A
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: N/A
Function Summary
- Entrez Summary: N/A
- UniProt Summary: Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion. {ECO:0000269|PubMed:10085077, ECO:0000269|PubMed:23667509}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 5345
- Expression level (log2 read counts): -1.82