TOMM40L

Entrez Summary: N/A
UniProt Summary: Potential channel-forming protein implicated in import of protein precursors into mitochondria. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

preprotein binding
mitochondrion targeting sequence binding
porin activity
mitochondrial outer membrane translocase complex
pore complex
protein transmembrane transporter activity
protein import into mitochondrial matrix
protein transmembrane import into intracellular organelle
intracellular protein transmembrane transport
protein targeting to mitochondrion
protein transmembrane transport
establishment of protein localization to mitochondrion
protein localization to mitochondrion
mitochondrial transmembrane transport
protein import
mitochondrial transport
protein targeting
establishment of protein localization to organelle
mitochondrion organization
protein-containing complex
protein localization to organelle
molecular function
intracellular protein transport
transmembrane transport
ion transport
protein transport
intracellular transport
peptide transport
amide transport
cellular protein localization
cellular macromolecule localization
establishment of protein localization
establishment of localization in cell
nitrogen compound transport