TRAF3IP3

Gene Information
  • Official Symbol: TRAF3IP3
  • Official Name: TRAF3 interacting protein 3
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 80342
  • UniProt: Q9Y228
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: The gene encodes a protein that mediates cell growth by modulating the c-Jun N-terminal kinase signal transduction pathway. The encoded protein may also interact with a large multi-protein assembly containing the phosphatase 2A catalytic subunit. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013].
  • UniProt Summary: May function as an adapter molecule that regulates TRAF3-mediated JNK activation. {ECO:0000250}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 13803
  • Expression level (log2 read counts): 2.67

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1