TRDMT1

Entrez Summary: N/A
UniProt Summary: Specifically methylates cytosine 38 in the anticodon loop of tRNA(Asp). {ECO:0000269|PubMed:16424344}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/726

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/25
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/15
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/14
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/7
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

tRNA (cytosine-5-)-methyltransferase activity
tRNA methyltransferase activity
response to amphetamine
tRNA methylation
response to amine
response to bronchodilator
RNA methylation
tRNA modification
tRNA processing
RNA modification
tRNA metabolic process
macromolecule methylation
response to xenobiotic stimulus
methylation
ncRNA processing
ncRNA metabolic process
response to toxic substance
RNA processing
response to organonitrogen compound
response to drug
response to nitrogen compound
RNA binding
RNA metabolic process
gene expression