TYSND1

Entrez Summary: N/A
UniProt Summary: Peroxisomal protease that mediates both the removal of the leader peptide from proteins containing a PTS2 target sequence and processes several PTS1-containing proteins. Catalyzes the processing of PTS1-proteins involved in the peroxisomal beta- oxidation of fatty acids. {ECO:0000269|PubMed:22002062}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

regulation of fatty acid beta-oxidation
regulation of fatty acid oxidation
peroxisomal matrix
regulation of lipid catabolic process
protein targeting to peroxisome
protein localization to peroxisome
establishment of protein localization to peroxisome
peroxisomal transport
peroxisome organization
regulation of fatty acid metabolic process
protease binding
peroxisome
protein processing
serine-type endopeptidase activity
regulation of cellular ketone metabolic process
protein maturation
protein homooligomerization
protein targeting
regulation of lipid metabolic process
regulation of small molecule metabolic process
establishment of protein localization to organelle
protein complex oligomerization
protein localization to organelle
regulation of cellular catabolic process
intracellular protein transport
regulation of catabolic process
proteolysis
protein transport
intracellular transport
peptide transport
protein-containing complex assembly
amide transport
cellular protein localization
cellular macromolecule localization
establishment of protein localization
establishment of localization in cell
nitrogen compound transport
protein-containing complex subunit organization
membrane
gene expression