UBAC2
Gene Information
- Official Symbol: UBAC2
- Official Name: UBA domain containing 2
- Aliases and Previous Symbols: N/A
- Entrez ID: 337867
- UniProt: Q8NBM4
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
| UBA |
GO Terms
| negative regulation of retrograde protein transport, ER to cytosol |
| negative regulation of protein exit from endoplasmic reticulum |
| negative regulation of ERAD pathway |
| regulation of retrograde protein transport, ER to cytosol |
| regulation of protein exit from endoplasmic reticulum |
| regulation of ERAD pathway |
| negative regulation of intracellular protein transport |
| negative regulation of response to endoplasmic reticulum stress |
| negative regulation of proteasomal protein catabolic process |
| negative regulation of intracellular transport |
| negative regulation of proteolysis involved in cellular protein catabolic process |
| regulation of response to endoplasmic reticulum stress |
| negative regulation of cellular protein catabolic process |
| negative regulation of cellular protein localization |
| negative regulation of protein catabolic process |
| protein localization to endoplasmic reticulum |
| negative regulation of protein transport |
| regulation of proteasomal protein catabolic process |
| negative regulation of establishment of protein localization |
| regulation of proteolysis involved in cellular protein catabolic process |
| regulation of intracellular protein transport |
| regulation of cellular protein catabolic process |
| negative regulation of cellular catabolic process |
| negative regulation of catabolic process |
| regulation of intracellular transport |
| negative regulation of proteolysis |
| regulation of protein catabolic process |
| negative regulation of transport |
| regulation of cellular protein localization |
| regulation of protein transport |
| regulation of proteolysis |
| regulation of cellular response to stress |
| protein localization to organelle |
| regulation of peptide transport |
| regulation of establishment of protein localization |
| regulation of cellular catabolic process |
| regulation of cellular localization |
| endoplasmic reticulum membrane |
| regulation of catabolic process |
| endoplasmic reticulum |
| regulation of protein localization |
| negative regulation of cellular protein metabolic process |
| negative regulation of protein metabolic process |
| regulation of response to stress |
| cellular protein localization |
| cellular macromolecule localization |
| negative regulation of response to stimulus |
| regulation of transport |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
| Screen | Score |
|---|---|
| TRAIL 50ng/ml R00 exp36 | 1.82 |
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 6620
- Expression level (log2 read counts): 5.68
Expression Distribution
UBAC2 Expression in NALM6 Cells: 5.68
