UBE2O

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 2/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	1/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	1/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

positive regulation of BMP signaling pathway
protein K63-linked ubiquitination
ubiquitin conjugating enzyme activity
protein monoubiquitination
regulation of BMP signaling pathway
retrograde transport, endosome to Golgi
positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
cytosolic transport
ubiquitin protein ligase activity
endosomal transport
regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
ubiquitin-protein transferase activity
regulation of cellular response to growth factor stimulus
nuclear body
protein polyubiquitination
protein ubiquitination
protein modification by small protein conjugation
protein modification by small protein conjugation or removal
RNA binding
ATP binding
intracellular transport
positive regulation of signal transduction
positive regulation of cell communication
positive regulation of signaling
establishment of localization in cell
vesicle-mediated transport