UGT3A2

Entrez Summary: N/A
UniProt Summary: UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds (By similarity). {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Glyco tran 28 C
UDPGT

cellular response to genistein
cellular response to phenylpropanoid
cellular response to hydroxyisoflavone
response to genistein
response to hydroxyisoflavone
response to phenylpropanoid
UDP-glycosyltransferase activity
glucuronosyltransferase activity
cellular response to ketone
response to antineoplastic agent
response to ketone
cellular response to drug
cellular response to organic cyclic compound
cellular response to hormone stimulus
intracellular membrane-bounded organelle
response to hormone
response to organic cyclic compound
response to drug
cellular response to oxygen-containing compound
cellular response to endogenous stimulus
response to endogenous stimulus
response to oxygen-containing compound