VSTM5

Gene Information
  • Official Symbol: VSTM5
  • Official Name: V-set and transmembrane domain containing 5
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 387804
  • UniProt: A8MXK1
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Cell adhesion-like membrane protein of the central nervous system (CNS) which modulates both the position and complexity of central neurons by altering their membrane morphology and dynamics. Involved in the formation of neuronal dendrites and protrusions including dendritic filopodia. In synaptogenesis, regulates synapse formation by altering dendritic spine morphology and actin distribution. Promotes formation of unstable neuronal spines such as thin and branched types. Regulates neuronal morphogenesis and migration during cortical development in the brain. {ECO:0000250|UniProtKB:Q9D806}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 17913
  • Expression level (log2 read counts): -2.74

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1