WIPF3

Entrez Summary: N/A
UniProt Summary: May be a regulator of cytoskeletal organization. May have a role in spermatogenesis (By similarity). {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

actin cortical patch assembly
actin cortical patch organization
actin cortical patch localization
actin cortical patch
cortical actin cytoskeleton organization
cortical cytoskeleton organization
actin filament
actin filament-based movement
SH3 domain binding
Fc-gamma receptor signaling pathway involved in phagocytosis
immune response-regulating cell surface receptor signaling pathway involved in phagocytosis
Fc receptor mediated stimulatory signaling pathway
Fc-gamma receptor signaling pathway
actin filament binding
Fc receptor signaling pathway
phagocytosis
immune response-activating cell surface receptor signaling pathway
immune response-regulating cell surface receptor signaling pathway
actin cytoskeleton organization
spermatogenesis
endocytosis
immune response-activating signal transduction
male gamete generation
actin filament-based process
immune response-regulating signaling pathway
activation of immune response
import into cell
gamete generation
multicellular organismal reproductive process
sexual reproduction
multicellular organism reproduction
positive regulation of immune response
multi-organism reproductive process
immune effector process
cytoskeleton organization
regulation of immune response
positive regulation of immune system process
reproductive process
reproduction
movement of cell or subcellular component