ZNF205

Gene Information

Official Symbol: ZNF205
Official Name: zinc finger protein 205
Aliases and Previous Symbols: N/A
Entrez ID: 7755
UniProt: O95201
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Function Summary

Entrez Summary: N/A
UniProt Summary: May be involved in transcriptional regulation.

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Essentiality in NALM6

Essentiality Rank: 4279
Expression level (log2 read counts): -2.21

Expression Distribution

zf-C2H2
KRAB

positive regulation of hydrogen peroxide biosynthetic process
positive regulation of hydrogen peroxide metabolic process
positive regulation of cofactor metabolic process
regulation of hydrogen peroxide biosynthetic process
regulation of hydrogen peroxide metabolic process
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
regulation of cofactor metabolic process
regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
positive regulation of reactive oxygen species biosynthetic process
regulation of mitochondrial membrane permeability
regulation of membrane permeability
regulation of reactive oxygen species biosynthetic process
positive regulation of reactive oxygen species metabolic process
positive regulation of mitochondrion organization
mitochondrial membrane organization
positive regulation of apoptotic signaling pathway
regulation of reactive oxygen species metabolic process
regulation of mitochondrion organization
mitochondrial transport
DNA-binding transcription repressor activity, RNA polymerase II-specific
RNA polymerase II regulatory region sequence-specific DNA binding
regulation of apoptotic signaling pathway
mitochondrion organization
positive regulation of organelle organization
positive regulation of apoptotic process
positive regulation of programmed cell death
positive regulation of cell death
zinc ion binding
membrane organization
negative regulation of transcription by RNA polymerase II
positive regulation of transport
negative regulation of transcription, DNA-templated
positive regulation of cellular component organization
negative regulation of nucleic acid-templated transcription
negative regulation of RNA biosynthetic process
mitochondrion
regulation of organelle organization
negative regulation of RNA metabolic process
negative regulation of cellular macromolecule biosynthetic process
negative regulation of nucleobase-containing compound metabolic process