Show pageOld revisionsBacklinksFold/unfold allBack to top This page is read only. You can view the source, but not change it. Ask your administrator if you think this is wrong. ====== Ethanol 0.01 R05 exp234 ====== ==== Mechanism of Action ==== Pleiotropic effects on membranes, ion channels, enzymes, receptors * **<color #00a2e8>Class / Subclass 1:</color>** Environmental Stresses / Solvent ==== Technical Notes ==== <accordion collapsed='true'> <panel title='Compound References' collapsed='true'> * **<color #00a2e8>PubChem Name:</color>** %%Ethanol%% * **<color #00a2e8>Synonyms:</color>** N/A * **<color #00a2e8>CAS #:</color>** 64-17-5 * **<color #00a2e8>PubChem CID:</color>** [[https://pubchem.ncbi.nlm.nih.gov/compound/702|702]] * **<color #00a2e8>IUPAC:</color>** %%ethanol%% * **<color #00a2e8>INCHI Name:</color>** InChI=1S/C2H6O/c1-2-3/h3H,2H2,1H3 * **<color #00a2e8>INCHI Key:</color>** LFQSCWFLJHTTHZ-UHFFFAOYSA-N * **<color #00a2e8>Molecular Weight:</color>** 46.07 * **<color #00a2e8>Canonical SMILES:</color>** CCO * **<color #00a2e8>Isomeric SMILES:</color>** N/A * **<color #00a2e8>Molecular Formula:</color>** C2H6O {{:chemogenomics:structures:chem-0139.svg?nolink}} </panel> <panel title='Compound Supplier' collapsed='true'> * **<color #00a2e8>Supplier Name:</color>** Les Alcools de Commerce * **<color #00a2e8>Catalog #:</color>** P016EAAN * **<color #00a2e8>Lot #:</color>** N/A </panel> <panel title='Compound Characterization' collapsed='true'> Characterization data not available. </panel> <panel title='Dose Response Curve' collapsed='true'> * **<color #00a2e8>Platform ID:</color>** EtOH * **<color #00a2e8>Min:</color>** -9.0156; **<color #00a2e8>Max:</color>** 4.5158 {{:chemogenomics:dose_response:dr_222.png?nolink&500 |}} \\ \\ \\ \\ |< 300px 100px 200px >| ^ IC ^ Concentration (µM) ^ | IC10 |N/A | | IC20 |N/A | | IC30 |N/A | | IC40 |N/A | | IC50 |N/A | | IC60 |N/A | | IC70 |N/A | | IC80 |N/A | | IC90 |N/A | \\ </panel> </accordion> ==== Screen Summary ==== * **<color #00a2e8>Round</color>**: 05 * **<color #00a2e8>Dose</color>**: 1% * **<color #00a2e8>Days of incubation</color>**: 8 * **<color #00a2e8>Doublings</color>**: 2.6 * **<color #00a2e8>Numbers of reads</color>**: 19333524 ==== Screen Results ==== ^Sensitive/Resistant hits (FDR<0.05)^CRANKS^Score Plot^Top 30 Genes^Screen Similarity^Top 30 Sensitive GO terms^Top 30 Resistant GO terms^ |27/78|<color #e85500>[[https://files.tyerslab.com/files/public/chemogenomics/cranks/Ethanol_1pc_Round-5_exp234.txt|Scores]]</color>|<button type="primary" size="sm" modal="ScorePlot">View</button>|<button type="primary" size="sm" modal="modal_hits">View</button>|<button type="primary" size="sm" modal="modal_screen_similarity">View</button>|<button type="default" size="sm" modal="modal_go_sensitive">View</button>|<button type="primary" size="sm" modal="modal_go_resistant">View</button>| <modal id='ScorePlot' size='lg' title='Ethanol 0.01 R05 exp234'> {{:chemogenomics:cranks_plots:exp234.png?nolink}} </modal> <modal id="modal_hits" size="sm" title="Top 30 S/R Genes"> ^Gene^CRANKS Score^FDR^ |[[:human_genes:B:BCL2|BCL2]]|-3.40|<0.01| |[[:human_genes:S:SEC31A|SEC31A]]|-3.11|<0.01| |[[:human_genes:W:WSB1|WSB1]]|-2.94|0.02| |[[:human_genes:D:DERL2|DERL2]]|-2.83|0.02| |[[:human_genes:D:DNAJC3|DNAJC3]]|-2.79|0.02| |[[:human_genes:D:DERL1|DERL1]]|-2.79|0.02| |[[:human_genes:N:NGLY1|NGLY1]]|-2.78|0.02| |[[:human_genes:D:DPAGT1|DPAGT1]]|-2.75|0.02| |[[:human_genes:R:RCE1|RCE1]]|-2.62|0.02| |[[:human_genes:S:SMG8|SMG8]]|-2.61|0.02| |[[:human_genes:R:RHOA|RHOA]]|-2.61|0.02| |[[:human_genes:F:FAM13B|FAM13B]]|-2.61|0.02| |[[:human_genes:A:ALG9|ALG9]]|-2.58|0.02| |[[:human_genes:G:GNA13|GNA13]]|-2.57|0.02| |[[:human_genes:C:CSK|CSK]]|-2.54|0.06| |[[:human_genes:F:FXR1|FXR1]]|-2.54|0.02| |[[:human_genes:S:SRSF5|SRSF5]]|-2.54|0.02| |[[:human_genes:I:IRF4|IRF4]]|-2.50|0.02| |[[:human_genes:A:AIP|AIP]]|-2.49|0.02| |[[:human_genes:S:SEC24C|SEC24C]]|-2.48|0.02| |[[:human_genes:A:ATG9A|ATG9A]]|-2.47|0.02| |[[:human_genes:B:BACH2|BACH2]]|-2.47|0.04| |[[:human_genes:S:SH3GL1|SH3GL1]]|-2.46|0.04| |[[:human_genes:U:USO1|USO1]]|-2.44|0.05| |[[:human_genes:Z:ZFP28|ZFP28]]|-2.42|0.03| |[[:human_genes:Z:ZC3H18|ZC3H18]]|-2.40|0.13| |[[:human_genes:S:STT3A|STT3A]]|-2.40|0.08| |[[:human_genes:I:IVL|IVL]]|-2.39|0.09| |[[:human_genes:B:BCL2L1|BCL2L1]]|-2.38|0.04| |[[:human_genes:M:MBTPS1|MBTPS1]]|-2.37|0.09| |[[:human_genes:E:EIF3G|EIF3G]]|3.05|<0.01| |[[:human_genes:B:BRMS1|BRMS1]]|3.08|<0.01| |[[:human_genes:P:PDPK1|PDPK1]]|3.13|<0.01| |[[:human_genes:C:CNOT2|CNOT2]]|3.15|<0.01| |[[:human_genes:S:SRM|SRM]]|3.19|<0.01| |[[:human_genes:Z:ZNF207|ZNF207]]|3.44|<0.01| |[[:human_genes:M:MCL1|MCL1]]|3.46|<0.01| |[[:human_genes:C:CD81|CD81]]|3.48|<0.01| |[[:human_genes:P:PLAA|PLAA]]|3.63|<0.01| |[[:human_genes:A:AKT1|AKT1]]|3.74|<0.01| |[[:human_genes:H:HEXIM1|HEXIM1]]|3.77|<0.01| |[[:human_genes:C:CD19|CD19]]|3.86|<0.01| |[[:human_genes:P:PRRC2C|PRRC2C]]|4.11|<0.01| |[[:human_genes:P:PTMA|PTMA]]|4.14|<0.01| |[[:human_genes:R:RHOH|RHOH]]|4.15|<0.01| |[[:human_genes:U:UBQLN1|UBQLN1]]|4.38|<0.01| |[[:human_genes:P:PIK3CD|PIK3CD]]|4.39|<0.01| |[[:human_genes:M:MLST8|MLST8]]|4.40|<0.01| |[[:human_genes:P:PDS5A|PDS5A]]|4.51|<0.01| |[[:human_genes:A:ARRDC3|ARRDC3]]|4.74|<0.01| |[[:human_genes:P:PMAIP1|PMAIP1]]|4.75|<0.01| |[[:human_genes:V:VDAC2|VDAC2]]|4.84|<0.01| |[[:human_genes:A:ARID4B|ARID4B]]|5.29|<0.01| |[[:human_genes:M:MARCH5|MARCH5]]|5.56|<0.01| |[[:human_genes:K:KMT2D|KMT2D]]|5.66|<0.01| |[[:human_genes:B:BCL2L11|BCL2L11]]|5.72|<0.01| |[[:human_genes:R:RICTOR|RICTOR]]|6.11|<0.01| |[[:human_genes:M:MAPKAP1|MAPKAP1]]|6.36|<0.01| |[[:human_genes:D:DDX3X|DDX3X]]|7.12|<0.01| |[[:human_genes:B:BAK1|BAK1]]|8.00|<0.01| </modal> <modal id="modal_screen_similarity" size="lg" title="Correlated Screens"> ^Screen^Correlation^Plot^ |[[:results:exp134|MS023 2μM R03 exp134]]|0.126|<button type="primary" size="small" modal="1">View</button>| |[[:results:exp498|Lead acetate 2000μM R08 exp498 no dilution day6]]|0.108|<button type="primary" size="small" modal="2">View</button>| |[[:results:exp489|Hippuristanol 0.12μM R08 exp489 no dilution day6]]|0.104|<button type="primary" size="small" modal="3">View</button>| |[[:results:exp497|Lead acetate 2000μM R08 exp497]]|0.1|<button type="primary" size="small" modal="4">View</button>| |[[:results:exp488|Hippuristanol 0.12μM R08 exp488]]|0.1|<button type="primary" size="small" modal="5">View</button>| |[[:results:exp505|ML-792 0.2μM R08 exp505]]|0.095|<button type="primary" size="small" modal="6">View</button>| |[[:results:exp512|Olaparib 4μM R08 exp512]]|0.093|<button type="primary" size="small" modal="7">View</button>| |[[:results:exp407|Thapsigargin 0.005μM R07 exp407]]|0.083|<button type="primary" size="small" modal="8">View</button>| |[[:results:exp525|Sulforaphane 9μM R08 exp525]]|0.08|<button type="primary" size="small" modal="9">View</button>| |[[:results:exp102|Nifuroxazide 5μM R03 exp102]]|0.077|<button type="primary" size="small" modal="10">View</button>| |[[:results:exp535|Trimetrexate 0.03μM R08 exp535]]|0.074|<button type="primary" size="small" modal="11">View</button>| |[[:results:exp524|Staurosporine 0.02μM R08 exp524]]|0.073|<button type="primary" size="small" modal="12">View</button>| |[[:results:exp374|Latrunculin-B 10μM R07 exp374]]|0.069|<button type="primary" size="small" modal="13">View</button>| |[[:results:exp210|LB-100 2μM R05 exp210]]|0.069|<button type="primary" size="small" modal="14">View</button>| |[[:results:exp485|GSK626616 14μM R08 exp485]]|0.065|<button type="primary" size="small" modal="15">View</button>| |[[:results:exp21|MLN-4924 0.2μM R00 exp21]]|0.065|<button type="primary" size="small" modal="16">View</button>| |[[:results:exp135|MS023 7μM R03 exp135]]|0.065|<button type="primary" size="small" modal="17">View</button>| |[[:results:exp435|JQ1 0.8μM R08 exp435]]|0.064|<button type="primary" size="small" modal="18">View</button>| |[[:results:exp500|LY2090314 0.003μM R08 exp500 no dilution day6]]|0.061|<button type="primary" size="small" modal="19">View</button>| |[[:results:exp444|THZ531 0.225μM R08 exp444]]|0.06|<button type="primary" size="small" modal="20">View</button>| |[[:results:exp526|Sulforaphane 9μM R08 exp526 no dilution day6]]|0.059|<button type="primary" size="small" modal="21">View</button>| |[[:results:exp492|iCRT14 30μM R08 exp492]]|0.058|<button type="primary" size="small" modal="22">View</button>| |[[:results:exp30|Rapamycin 10μM R00 exp30]]|0.056|<button type="primary" size="small" modal="23">View</button>| |[[:results:exp499|LY2090314 0.003μM R08 exp499]]|0.056|<button type="primary" size="small" modal="24">View</button>| |[[:results:exp80|RO-3307 4.7μM R02 exp80]]|0.055|<button type="primary" size="small" modal="25">View</button>| |[[:results:exp85|UM0129480 7μM R02 exp85]]|0.055|<button type="primary" size="small" modal="26">View</button>| |[[:results:exp240|Pyridostatin 4μM R05 exp240]]|0.052|<button type="primary" size="small" modal="27">View</button>| |[[:results:exp456|Benzoate 20000μM R08 exp456]]|0.097|<button type="primary" size="small" modal="28">View</button>| |[[:results:exp116|AICAR 240μM R03 exp116]]|0.093|<button type="primary" size="small" modal="29">View</button>| |[[:results:exp455|Benzoate 10000μM R08 exp455]]|0.082|<button type="primary" size="small" modal="30">View</button>| |[[:results:exp440|Aphidicolin 0.4μM R08 exp440]]|0.08|<button type="primary" size="small" modal="31">View</button>| |[[:results:exp274|Citral 50μM R06 exp274]]|0.079|<button type="primary" size="small" modal="32">View</button>| |[[:results:exp6|Bortezomib 0.005μM R00 exp6]]|0.075|<button type="primary" size="small" modal="33">View</button>| |[[:results:exp468|CB-5083 0.4μM R08 exp468]]|0.073|<button type="primary" size="small" modal="34">View</button>| |[[:results:exp214|2-Deoxy-D-glucose 800μM R05 exp214]]|0.067|<button type="primary" size="small" modal="35">View</button>| |[[:results:exp216|Erlotinib 10μM R05 exp216]]|0.062|<button type="primary" size="small" modal="36">View</button>| |[[:results:exp355|Dinaciclib 0.007μM R07 exp355]]|0.059|<button type="primary" size="small" modal="37">View</button>| |[[:results:exp211|AICAR 240μM R05 exp211]]|0.058|<button type="primary" size="small" modal="38">View</button>| |[[:results:exp259|6-Thio-2-deoxyguanosine 2μM R06 exp259]]|0.057|<button type="primary" size="small" modal="39">View</button>| |[[:results:exp233|EPZ-5676 30μM R05 exp233]]|0.056|<button type="primary" size="small" modal="40">View</button>| |[[:results:exp222|Betulinic acid 10 to 15μM on day4 R05 exp222]]|0.055|<button type="primary" size="small" modal="41">View</button>| |[[:results:exp275|Citral 75μM R06 exp275]]|0.054|<button type="primary" size="small" modal="42">View</button>| |[[:results:exp453|B02 10μM R08 exp453]]|0.053|<button type="primary" size="small" modal="43">View</button>| |[[:results:exp452|Azithromycin 100μM R08 exp452]]|0.052|<button type="primary" size="small" modal="44">View</button>| |[[:results:exp354|Diepoxybutane 3μM R07 exp354]]|0.052|<button type="primary" size="small" modal="45">View</button>| |[[:results:exp334|All-trans-Retinoic-Acid 40μM R07 exp334]]|0.051|<button type="primary" size="small" modal="46">View</button>| </modal> <modal id="1" size="lg" title="Ethanol 0.01 R05 exp234 vs MS023 2μM R03 exp134"> {{:chemogenomics:comparison_plots:exp134_vs_exp234.png?nolink |}} </modal> <modal id="2" size="lg" title="Ethanol 0.01 R05 exp234 vs Lead acetate 2000μM R08 exp498 no dilution day6"> {{:chemogenomics:comparison_plots:exp234_vs_exp498.png?nolink |}} </modal> <modal id="3" size="lg" title="Ethanol 0.01 R05 exp234 vs Hippuristanol 0.12μM R08 exp489 no dilution day6"> {{:chemogenomics:comparison_plots:exp234_vs_exp489.png?nolink |}} </modal> <modal id="4" size="lg" title="Ethanol 0.01 R05 exp234 vs Lead acetate 2000μM R08 exp497"> {{:chemogenomics:comparison_plots:exp234_vs_exp497.png?nolink |}} </modal> <modal id="5" size="lg" title="Ethanol 0.01 R05 exp234 vs Hippuristanol 0.12μM R08 exp488"> {{:chemogenomics:comparison_plots:exp234_vs_exp488.png?nolink |}} </modal> <modal id="6" size="lg" title="Ethanol 0.01 R05 exp234 vs ML-792 0.2μM R08 exp505"> {{:chemogenomics:comparison_plots:exp234_vs_exp505.png?nolink |}} </modal> <modal id="7" size="lg" title="Ethanol 0.01 R05 exp234 vs Olaparib 4μM R08 exp512"> {{:chemogenomics:comparison_plots:exp234_vs_exp512.png?nolink |}} </modal> <modal id="8" size="lg" title="Ethanol 0.01 R05 exp234 vs Thapsigargin 0.005μM R07 exp407"> {{:chemogenomics:comparison_plots:exp234_vs_exp407.png?nolink |}} </modal> <modal id="9" size="lg" title="Ethanol 0.01 R05 exp234 vs Sulforaphane 9μM R08 exp525"> {{:chemogenomics:comparison_plots:exp234_vs_exp525.png?nolink |}} </modal> <modal id="10" size="lg" title="Ethanol 0.01 R05 exp234 vs Nifuroxazide 5μM R03 exp102"> {{:chemogenomics:comparison_plots:exp102_vs_exp234.png?nolink |}} </modal> <modal id="11" size="lg" title="Ethanol 0.01 R05 exp234 vs Trimetrexate 0.03μM R08 exp535"> {{:chemogenomics:comparison_plots:exp234_vs_exp535.png?nolink |}} </modal> <modal id="12" size="lg" title="Ethanol 0.01 R05 exp234 vs Staurosporine 0.02μM R08 exp524"> {{:chemogenomics:comparison_plots:exp234_vs_exp524.png?nolink |}} </modal> <modal id="13" size="lg" title="Ethanol 0.01 R05 exp234 vs Latrunculin-B 10μM R07 exp374"> {{:chemogenomics:comparison_plots:exp234_vs_exp374.png?nolink |}} </modal> <modal id="14" size="lg" title="Ethanol 0.01 R05 exp234 vs LB-100 2μM R05 exp210"> {{:chemogenomics:comparison_plots:exp210_vs_exp234.png?nolink |}} </modal> <modal id="15" size="lg" title="Ethanol 0.01 R05 exp234 vs GSK626616 14μM R08 exp485"> {{:chemogenomics:comparison_plots:exp234_vs_exp485.png?nolink |}} </modal> <modal id="16" size="lg" title="Ethanol 0.01 R05 exp234 vs MLN-4924 0.2μM R00 exp21"> {{:chemogenomics:comparison_plots:exp21_vs_exp234.png?nolink |}} </modal> <modal id="17" size="lg" title="Ethanol 0.01 R05 exp234 vs MS023 7μM R03 exp135"> {{:chemogenomics:comparison_plots:exp135_vs_exp234.png?nolink |}} </modal> <modal id="18" size="lg" title="Ethanol 0.01 R05 exp234 vs JQ1 0.8μM R08 exp435"> {{:chemogenomics:comparison_plots:exp234_vs_exp435.png?nolink |}} </modal> <modal id="19" size="lg" title="Ethanol 0.01 R05 exp234 vs LY2090314 0.003μM R08 exp500 no dilution day6"> {{:chemogenomics:comparison_plots:exp234_vs_exp500.png?nolink |}} </modal> <modal id="20" size="lg" title="Ethanol 0.01 R05 exp234 vs THZ531 0.225μM R08 exp444"> {{:chemogenomics:comparison_plots:exp234_vs_exp444.png?nolink |}} </modal> <modal id="21" size="lg" title="Ethanol 0.01 R05 exp234 vs Sulforaphane 9μM R08 exp526 no dilution day6"> {{:chemogenomics:comparison_plots:exp234_vs_exp526.png?nolink |}} </modal> <modal id="22" size="lg" title="Ethanol 0.01 R05 exp234 vs iCRT14 30μM R08 exp492"> {{:chemogenomics:comparison_plots:exp234_vs_exp492.png?nolink |}} </modal> <modal id="23" size="lg" title="Ethanol 0.01 R05 exp234 vs Rapamycin 10μM R00 exp30"> {{:chemogenomics:comparison_plots:exp234_vs_exp30.png?nolink |}} </modal> <modal id="24" size="lg" title="Ethanol 0.01 R05 exp234 vs LY2090314 0.003μM R08 exp499"> {{:chemogenomics:comparison_plots:exp234_vs_exp499.png?nolink |}} </modal> <modal id="25" size="lg" title="Ethanol 0.01 R05 exp234 vs RO-3307 4.7μM R02 exp80"> {{:chemogenomics:comparison_plots:exp234_vs_exp80.png?nolink |}} </modal> <modal id="26" size="lg" title="Ethanol 0.01 R05 exp234 vs UM0129480 7μM R02 exp85"> {{:chemogenomics:comparison_plots:exp234_vs_exp85.png?nolink |}} </modal> <modal id="27" size="lg" title="Ethanol 0.01 R05 exp234 vs Pyridostatin 4μM R05 exp240"> {{:chemogenomics:comparison_plots:exp234_vs_exp240.png?nolink |}} </modal> <modal id="28" size="lg" title="Benzoate 20000μM R08 exp456 vs Ethanol 0.01 R05 exp234"> {{:chemogenomics:comparison_plots:exp234_vs_exp456.png?nolink |}} </modal> <modal id="29" size="lg" title="AICAR 240μM R03 exp116 vs Ethanol 0.01 R05 exp234"> {{:chemogenomics:comparison_plots:exp116_vs_exp234.png?nolink |}} </modal> <modal id="30" size="lg" title="Benzoate 10000μM R08 exp455 vs Ethanol 0.01 R05 exp234"> {{:chemogenomics:comparison_plots:exp234_vs_exp455.png?nolink |}} </modal> <modal id="31" size="lg" title="Aphidicolin 0.4μM R08 exp440 vs Ethanol 0.01 R05 exp234"> {{:chemogenomics:comparison_plots:exp234_vs_exp440.png?nolink |}} </modal> <modal id="32" size="lg" title="Citral 50μM R06 exp274 vs Ethanol 0.01 R05 exp234"> {{:chemogenomics:comparison_plots:exp234_vs_exp274.png?nolink |}} </modal> <modal id="33" size="lg" title="Bortezomib 0.005μM R00 exp6 vs Ethanol 0.01 R05 exp234"> {{:chemogenomics:comparison_plots:exp234_vs_exp6.png?nolink |}} </modal> <modal id="34" size="lg" title="CB-5083 0.4μM R08 exp468 vs Ethanol 0.01 R05 exp234"> {{:chemogenomics:comparison_plots:exp234_vs_exp468.png?nolink |}} </modal> <modal id="35" size="lg" title="2-Deoxy-D-glucose 800μM R05 exp214 vs Ethanol 0.01 R05 exp234"> {{:chemogenomics:comparison_plots:exp214_vs_exp234.png?nolink |}} </modal> <modal id="36" size="lg" title="Erlotinib 10μM R05 exp216 vs Ethanol 0.01 R05 exp234"> {{:chemogenomics:comparison_plots:exp216_vs_exp234.png?nolink |}} </modal> <modal id="37" size="lg" title="Dinaciclib 0.007μM R07 exp355 vs Ethanol 0.01 R05 exp234"> {{:chemogenomics:comparison_plots:exp234_vs_exp355.png?nolink |}} </modal> <modal id="38" size="lg" title="AICAR 240μM R05 exp211 vs Ethanol 0.01 R05 exp234"> {{:chemogenomics:comparison_plots:exp211_vs_exp234.png?nolink |}} </modal> <modal id="39" size="lg" title="6-Thio-2-deoxyguanosine 2μM R06 exp259 vs Ethanol 0.01 R05 exp234"> {{:chemogenomics:comparison_plots:exp234_vs_exp259.png?nolink |}} </modal> <modal id="40" size="lg" title="EPZ-5676 30μM R05 exp233 vs Ethanol 0.01 R05 exp234"> {{:chemogenomics:comparison_plots:exp233_vs_exp234.png?nolink |}} </modal> <modal id="41" size="lg" title="Betulinic acid 10 to 15μM on day4 R05 exp222 vs Ethanol 0.01 R05 exp234"> {{:chemogenomics:comparison_plots:exp222_vs_exp234.png?nolink |}} </modal> <modal id="42" size="lg" title="Citral 75μM R06 exp275 vs Ethanol 0.01 R05 exp234"> {{:chemogenomics:comparison_plots:exp234_vs_exp275.png?nolink |}} </modal> <modal id="43" size="lg" title="B02 10μM R08 exp453 vs Ethanol 0.01 R05 exp234"> {{:chemogenomics:comparison_plots:exp234_vs_exp453.png?nolink |}} </modal> <modal id="44" size="lg" title="Azithromycin 100μM R08 exp452 vs Ethanol 0.01 R05 exp234"> {{:chemogenomics:comparison_plots:exp234_vs_exp452.png?nolink |}} </modal> <modal id="45" size="lg" title="Diepoxybutane 3μM R07 exp354 vs Ethanol 0.01 R05 exp234"> {{:chemogenomics:comparison_plots:exp234_vs_exp354.png?nolink |}} </modal> <modal id="46" size="lg" title="All-trans-Retinoic-Acid 40μM R07 exp334 vs Ethanol 0.01 R05 exp234"> {{:chemogenomics:comparison_plots:exp234_vs_exp334.png?nolink |}} </modal> <modal id="modal_go_sensitive" size="lg" title="Top 30 sensitive GO terms">No GO term hits below threshold. (FDR <0.05)</modal> <modal id="modal_go_resistant" size="lg" title="Top 30 resistant GO terms"> ^GO Term^Fold Change^Genes^ |Bcl-2 family protein complex|245.48|BAK1,BCL2L11,PMAIP1,MCL1| |TORC2 complex|207.13|MAPKAP1,RICTOR,MLST8| |positive regulation of response to endoplasmic reticulum stress|63.12|BAK1,BCL2L11,PMAIP1,UBQLN1| |apoptotic mitochondrial changes|59.18|BAK1,BCL2L11,VDAC2,PMAIP1,AKT1,MCL1| |regulation of release of cytochrome c from mitochondria|50.21|BAK1,BCL2L11,PMAIP1,AKT1| |regulation of mitochondrial membrane permeability|40.17|BAK1,BCL2L11,VDAC2,PMAIP1| |extrinsic apoptotic signaling pathway|25.11|BAK1,DDX3X,BCL2L11,MCL1,PDPK1| |regulation of intrinsic apoptotic signaling pathway|22.22|DDX3X,BCL2L11,VDAC2,PMAIP1,UBQLN1,AKT1,MCL1| |positive regulation of cell growth|21.38|DDX3X,MAPKAP1,RICTOR,MLST8,AKT1,PLAA| |mitochondrial outer membrane|16.01|BAK1,BCL2L11,MARCHF5,VDAC2,PMAIP1,MCL1| |organelle outer membrane|14.10|BAK1,BCL2L11,MARCHF5,VDAC2,PMAIP1,MCL1| |outer membrane|13.92|BAK1,BCL2L11,MARCHF5,VDAC2,PMAIP1,MCL1| |positive regulation of growth|13.75|DDX3X,MAPKAP1,RICTOR,MLST8,AKT1,PLAA| |kinase regulator activity|13.20|DDX3X,RICTOR,MLST8,RHOH,HEXIM1,AKT1| |apoptotic signaling pathway|12.55|BAK1,DDX3X,BCL2L11,VDAC2,PMAIP1,MCL1,PDPK1| |regulation of apoptotic signaling pathway|11.78|BAK1,DDX3X,BCL2L11,VDAC2,PMAIP1,UBQLN1,AKT1,MCL1| |positive regulation of intracellular signal transduction|6.80|DDX3X,RICTOR,BCL2L11,PMAIP1,ARRDC3,MLST8,PIK3CD,HEXIM1,AKT1,CD81,MCL1,PDPK1| |negative regulation of apoptotic process|6.36|BAK1,DDX3X,MAPKAP1,RICTOR,VDAC2,MLST8,PTMA,AKT1,MCL1,PDPK1| |negative regulation of programmed cell death|6.18|BAK1,DDX3X,MAPKAP1,RICTOR,VDAC2,MLST8,PTMA,AKT1,MCL1,PDPK1| </modal> Last modified: 2026/01/15 21:36by 127.0.0.1