ACOX3

Entrez Summary: N/A
UniProt Summary: Oxidizes the CoA-esters of 2-methyl-branched fatty acids. {ECO:0000250, ECO:0000269|PubMed:9271077}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 1/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	1/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

ACOX
Acyl-CoA dh M

pristanoyl-CoA oxidase activity
acyl-CoA oxidase activity
fatty acid beta-oxidation using acyl-CoA oxidase
fatty acid binding
FAD binding
peroxisomal matrix
fatty acid beta-oxidation
flavin adenine dinucleotide binding
establishment of protein localization to peroxisome
protein localization to peroxisome
protein targeting to peroxisome
peroxisomal transport
fatty acid oxidation
lipid oxidation
peroxisome organization
fatty acid catabolic process
peroxisome
monocarboxylic acid catabolic process
lipid homeostasis
cellular lipid catabolic process
lipid modification
organic acid catabolic process
carboxylic acid catabolic process
lipid catabolic process
fatty acid metabolic process
protein targeting
establishment of protein localization to organelle
small molecule catabolic process
monocarboxylic acid metabolic process
protein localization to organelle
carboxylic acid metabolic process
cellular lipid metabolic process
oxidation-reduction process
intracellular protein transport
oxoacid metabolic process
organic acid metabolic process
chemical homeostasis
lipid metabolic process
protein transport
intracellular transport