ADAL

Entrez Summary: N/A
UniProt Summary: Putative nucleoside deaminase. May catalyze the hydrolytic deamination of adenosine or some similar substrate and play a role in purine metabolism (By similarity). {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

inosine biosynthetic process
adenosine catabolic process
adenosine deaminase activity
inosine metabolic process
purine ribonucleoside catabolic process
purine nucleoside catabolic process
adenosine metabolic process
purine-containing compound salvage
purine nucleoside biosynthetic process
purine ribonucleoside biosynthetic process
ribonucleoside biosynthetic process
ribonucleoside catabolic process
nucleoside catabolic process
cellular metabolic compound salvage
nucleoside biosynthetic process
glycosyl compound biosynthetic process
glycosyl compound catabolic process
nucleobase-containing small molecule catabolic process
purine-containing compound catabolic process
purine ribonucleoside metabolic process
purine nucleoside metabolic process
ribonucleoside metabolic process
nucleobase-containing small molecule biosynthetic process
nucleoside metabolic process
glycosyl compound metabolic process
drug catabolic process
purine-containing compound biosynthetic process
carbohydrate derivative catabolic process
purine-containing compound metabolic process
nucleobase-containing compound catabolic process
heterocycle catabolic process
cellular nitrogen compound catabolic process
small molecule catabolic process
aromatic compound catabolic process
nucleotide metabolic process
nucleoside phosphate metabolic process
organic cyclic compound catabolic process
drug metabolic process
nucleobase-containing small molecule metabolic process
small molecule biosynthetic process