AHNAK
Gene Information
- Official Symbol: AHNAK
- Official Name: AHNAK nucleoprotein
- Aliases and Previous Symbols: N/A
- Entrez ID: 79026
- UniProt: Q09666
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: The protein encoded by this gene is a large (700 kDa) structural scaffold protein consisting of a central domain with 128 aa repeats. The encoded protein may play a role in such diverse processes as blood-brain barrier formation, cell structure and migration, cardiac calcium channel regulation, and tumor metastasis. A much shorter variant encoding a 17 kDa isoform exists for this gene, and the shorter isoform initiates a feedback loop that regulates alternative splicing of this gene. [provided by RefSeq, Oct 2016].
- UniProt Summary: May be required for neuronal cell differentiation.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 8307
- Expression level (log2 read counts): -1.79