ANXA11

Entrez Summary: N/A
UniProt Summary: Binds specifically to calcyclin in a calcium-dependent manner (By similarity). Required for midbody formation and completion of the terminal phase of cytokinesis. {ECO:0000250, ECO:0000269|PubMed:15197175}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

phosphatidylethanolamine binding
azurophil granule
specific granule
S100 protein binding
MHC class II protein complex binding
cytokinetic process
calcium-dependent phospholipid binding
phagocytic vesicle
calcium-dependent protein binding
cytokinesis
melanosome
spindle
response to calcium ion
midbody
nuclear envelope
phagocytosis
collagen-containing extracellular matrix
response to metal ion
cell division
response to inorganic substance
calcium ion binding
cell cycle process
cell cycle
RNA binding
vesicle-mediated transport
membrane