AP3M2
Gene Information
- Official Symbol: AP3M2
- Official Name: adaptor related protein complex 3 subunit mu 2
- Aliases and Previous Symbols: N/A
- Entrez ID: 10947
- UniProt: P53677
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 8691
- Expression level (log2 read counts): 5.18