APBB2

• Official Symbol: APBB2
• Official Name: amyloid beta precursor protein binding family B member 2
• Aliases and Previous Symbols: N/A
• Entrez ID: 323
• UniProt: Q92870
• Interactions: BioGRID
• PubMed articles: Open PubMed
• OMIM: Open OMIM

• Entrez Summary: The protein encoded by this gene interacts with the cytoplasmic domains of amyloid beta (A4) precursor protein and amyloid beta (A4) precursor-like protein 2. This protein contains two phosphotyrosine binding (PTB) domains, which are thought to function in signal transduction. Polymorphisms in this gene have been associated with Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009].
• UniProt Summary: May modulate the internalization of amyloid-beta precursor protein.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

• Essentiality Rank: 5545
• Expression level (log2 read counts): 5.64

Expression Distribution

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APBB2 Expression in NALM6 Cells: 5.64