ARF3

Entrez Summary: N/A
UniProt Summary: GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP- ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Golgi to plasma membrane transport
retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
vesicle-mediated transport to the plasma membrane
post-Golgi vesicle-mediated transport
phosphatidylinositol biosynthetic process
phosphatidylinositol metabolic process
glycerophospholipid biosynthetic process
glycerolipid biosynthetic process
phospholipid biosynthetic process
glycerophospholipid metabolic process
GTPase activity
Golgi vesicle transport
phospholipid metabolic process
glycerolipid metabolic process
GTP binding
organophosphate biosynthetic process
lipid biosynthetic process
Golgi membrane
perinuclear region of cytoplasm
organophosphate metabolic process
cellular lipid metabolic process
Golgi apparatus
intracellular protein transport
lipid metabolic process
protein transport
intracellular transport
peptide transport
amide transport
cellular protein localization
cellular macromolecule localization
establishment of protein localization
establishment of localization in cell
nitrogen compound transport
vesicle-mediated transport