ARFIP2

Entrez Summary: N/A
UniProt Summary: Putative target protein of ADP-ribosylation factor. Involved in membrane ruffling.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

GTP-dependent protein binding
ruffle organization
phosphatidylinositol-4-phosphate binding
lamellipodium assembly
lamellipodium organization
Rac GTPase binding
ruffle
trans-Golgi network membrane
phospholipid binding
cell cortex
protein domain specific binding
cadherin binding
small GTPase mediated signal transduction
GTP binding
plasma membrane bounded cell projection assembly
cell projection assembly
actin cytoskeleton organization
actin filament-based process
intracellular protein transport
identical protein binding
cytoskeleton organization
plasma membrane bounded cell projection organization
cell projection organization
protein transport
intracellular transport
peptide transport
amide transport
cellular protein localization
cellular macromolecule localization
establishment of protein localization
intracellular signal transduction
establishment of localization in cell
nitrogen compound transport