ARHGAP15

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
UM0011500 10μM R05 exp246	-1.98
Vemurafenib 6.6μM R02 exp89	-1.74
ABT-702 5μM plus Dimethyloxaloylglycine 11μM R07 exp319	1.72
ABT-702 5μM R07 exp318	1.92

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

PH
RhoGAP

regulation of cell shape
GTPase activator activity
regulation of small GTPase mediated signal transduction
positive regulation of GTPase activity
regulation of GTPase activity
regulation of cell morphogenesis
positive regulation of hydrolase activity
regulation of anatomical structure morphogenesis
regulation of hydrolase activity
positive regulation of catalytic activity
positive regulation of molecular function
regulation of intracellular signal transduction
membrane