ARMC10

Gene Information
  • Official Symbol: ARMC10
  • Official Name: armadillo repeat containing 10
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 83787
  • UniProt: Q8N2F6
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: This gene encodes a protein that contains an armadillo repeat and transmembrane domain. The encoded protein decreases the transcriptional activity of the tumor suppressor protein p53 through direct interaction with the DNA-binding domain of p53, and may play a role in cell growth and survival. Upregulation of this gene may play a role in hepatocellular carcinoma. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3. [provided by RefSeq, Sep 2011].
  • UniProt Summary: N/A

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 14749
  • Expression level (log2 read counts): 5.92

Expression Distribution

  • Last modified: 2026/01/07 22:36
  • by 127.0.0.1