ARV1

Entrez Summary: this gene encodes a transmembrane protein that contains a conserved zinc ribbon motif at the N- terminus. A similar protein in mouse is thought to function in fatty acid homeostasis. Mutations in this gene are associated with early infantile epileptic encephalopathy 38. [provided by RefSeq, Nov 2016].
UniProt Summary: N/A

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

regulation of plasma membrane sterol distribution
cortical endoplasmic reticulum
regulation of intracellular lipid transport
regulation of intracellular cholesterol transport
regulation of intracellular sterol transport
sterol transporter activity
intracellular sterol transport
intracellular lipid transport
bile acid metabolic process
cholesterol biosynthetic process
secondary alcohol biosynthetic process
regulation of cholesterol transport
regulation of sterol transport
sterol biosynthetic process
regulation of membrane lipid distribution
cholesterol transport
regulation of cholesterol metabolic process
sterol transport
plasma membrane organization
regulation of lipid transport
alcohol biosynthetic process
regulation of steroid metabolic process
cholesterol metabolic process
steroid biosynthetic process
secondary alcohol metabolic process
sterol metabolic process
regulation of lipid localization
organic hydroxy compound transport
sphingolipid metabolic process
organic hydroxy compound biosynthetic process
membrane lipid metabolic process
steroid metabolic process
lipid transport
alcohol metabolic process
lipid localization
regulation of intracellular transport
regulation of lipid metabolic process
endomembrane system organization
regulation of small molecule metabolic process
organic hydroxy compound metabolic process