ASAP2
Gene Information
- Official Symbol: ASAP2
- Official Name: ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
- Aliases and Previous Symbols: N/A
- Entrez ID: 8853
- UniProt: O43150
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: Activates the small GTPases ARF1, ARF5 and ARF6. Regulates the formation of post-Golgi vesicles and modulates constitutive secretion. Modulates phagocytosis mediated by Fc gamma receptor and ARF6. Modulates PXN recruitment to focal contacts and cell migration. {ECO:0000269|PubMed:10022920, ECO:0000269|PubMed:10749932, ECO:0000269|PubMed:11304556}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 17536
- Expression level (log2 read counts): 3.36