ASAP3

Entrez Summary: N/A
UniProt Summary: Promotes cell proliferation. {ECO:0000269|PubMed:14654939}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
Heregulin-B 44ng/ml R08 exp486	-1.89
NMS-873 0.07μM R07 exp380	-1.87

regulation of stress fiber assembly
regulation of actomyosin structure organization
ruffle
regulation of actin filament bundle assembly
regulation of actin filament organization
GTPase activator activity
regulation of actin cytoskeleton organization
regulation of supramolecular fiber organization
regulation of actin filament-based process
positive regulation of GTPase activity
focal adhesion
regulation of GTPase activity
regulation of cytoskeleton organization
intracellular membrane-bounded organelle
positive regulation of hydrolase activity
regulation of cellular component biogenesis
cell migration
localization of cell
cell motility
regulation of hydrolase activity
regulation of organelle organization
locomotion
positive regulation of catalytic activity
movement of cell or subcellular component
positive regulation of molecular function